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Through this NOFO, the NCI encourages the submission
of exploratory/ developmental research grant (R21)
applications that focus on different aspects of cancer
control by modifying behavior, screening, and
understanding etiologic factors contributing to the
development of cancer, and developing ways to control
cancer.
The purpose of this NOFO is to encourage applications
seeking to develop the next generation of brain
stimulation devices for treating mental health disorders.
Applications are encouraged that will either 1) develop
novel brain stimulation devices or 2) significantly
enhance, by means of hardware/software
improvements, the effectiveness of brain stimulation
devices that are U.S. Food and Drug Administration
(FDA)-approved or cleared.
This NOFO invites Exploratory/ Developmental Research
Grant (R21) applications that propose to study the
ethical, legal and social implications (ELSI) of human
genetic or genomic research. Applications may propose
studies using either single or mixed methods, that break
new ground, extend previous discoveries in new
directions, or develop preliminary data in preparation for
larger studies.
The National Cancer Institute (NCI) invites applications
for support of investigator-initiated clinical trials related
to the programmatic interests of the NCI Division of
Cancer Prevention and/or the NCI Division of Cancer
Control and Population Sciences that have the potential
to reduce the burden of cancer through improvements in
early detection, screening, prevention and interception,
healthcare delivery, quality of life, and/or survivorship
related to cancer; with such attributes, the proposed
studies should also have the potential to improve clinical
practice and/or public health.
The proposed project must involve at least 1 clinical trial
related to the scientific interests of one or more of the
following research programs: Cancer Therapy Evaluation
Program, Cancer Imaging Program, Cancer Diagnosis
Program, Radiation Research Program, Complementary
and Alternative Medicine Program and/or the HIV and
AIDS Malignancies Research Programs. Applicants may
propose to conduct an early phase trial by itself, or in
combination with another research aim(s) as
appropriate.
The NCSBN Grant Program provides funding for
scientific research projects that advance the science of
nursing policy and regulation and build regulatory
expertise worldwide. Research Priorities include, but are
not limited to:
(1) Outcome studies related to nursing regulation;
(2) Nursing workforce;
(3) Substance use disorders in nursing;
(4) New technologies related to the profession;
(5) Regulatory implications of practice innovations/new
models of care delivery;
(6) LPN, RN and APRN scope of practice;
(7) Impact of policy on nursing
The Board will prioritize projects relating to
interventions on day of birth – including prevention of
stillborn
deaths. Priority will be given to applications that:
(1) Extend beyond local impact, demonstrating long-
term practical value and inspiring advancements in
other regions or countries;
(2) Have innovative approaches to more efficient
education and implementation;
(3) Present collaborative initiatives relating to scale-up
of proven concepts;
(4) Take place in the Foundation’s focus countries:
Tanzania, Ethiopia, Malawi, Bangladesh, India, and
Nepal.
This supports practically oriented research within its
stated 2025 strategy. Applications that relate to factors
2 and 3 of the Utstein Formula for Survival – improved
efficiency of education or implementation, are
particularly welcome. The Foundation supports projects
advancing resuscitation, trauma, and maternal/newborn
care.
Clinical Pilot and Feasibility Awards are offered to
support projects involving human subjects that will
develop and test new hypotheses and/or new methods
(or those being applied to the problems of cystic fibrosis
for the first time), and to support promising new
investigators as they establish themselves in research
areas relevant to cystic fibrosis. The intent of these
awards is to enable investigators to collect sufficient
preliminary data to determine the best strategies and
methods for approaching a major question that
ultimately will require assessment through a larger-scale
research and/or multi-center, collaborative trial.
The goal of this NOFO is to encourage applications for
studies that will enhance knowledge of mechanisms
associated with neuropsychiatric symptoms (NPS) in
persons with Alzheimer's disease (AD) or Alzheimer's
disease- related dementias (ADRD). The findings are
expected to advance mechanistic understanding of both
biobehavioral and neurobiological pathways leading to
NPS. Findings may also provide insight into novel
therapeutic targets that can be advanced into
interventions to treat and prevent the development of
NPS in AD and/or ADRD.
This NOFO will broadly focus on closing the treatment
gap for individuals with alcohol use disorder (AUD);
within this focus, there are five major areas of
emphasis: (1) increasing access to treatment for AUD,
(2) making treatment for AUD more appealing, (3)
examining cost structures and insurance systems, (4)
conducting studies on dissemination and implementation
of existing evidence-based approaches to treating AUD,
and (5) reducing health disparities as a means of
addressing the treatment gap in AUD for health disparity
populations.
This call aims to study the health inequities and/or
differences among under-studied PD communities,
across the spectrum of ethnicity, ancestry, geography,
socioeconomic conditions, and gender. Current research
has established the following: (1) Diagnosis of PD
among some under-studied communities is delayed; (2)
Some under-studied communities are less likely to
receive quality PD care; (3) Clinical trial enrollment
among certain under-studied communities does not
match their representation in the population; (4)
Differences in clinical features, response to treatment,
co-morbidities, prevalence, natural history, genetics and
biomarkers among various under-studied PD populations
have not been fully explored. Projects should address
one of these four issues. Projects can be designed to
detect inequities or differences, understand the reasons
for the inequities or differences, or test an intervention
to improve disparities.
This call supports research aimed at developing new
insights into the pathophysiology, etiology and/or
treatment of PD. Grant proposals can address research
questions anywhere along the pipeline from basic
science to rehabilitation-focused projects. APDA seeks to
promote the entry of new investigators into the field
of Parkinson research, as well as to support important
new ideas in the field worthy of investigation.
The Kyle Bryant Translational Research Award honors its
namesake for his diligent efforts to aid the rapid
translation of basic research discoveries into clinical
applications. Eligible applications should focus on
accelerating completion of translational stage activities
necessary for advancement to clinical study of a
therapeutic candidate or development of novel tools that
address a critical bottleneck to the discovery or
development of therapies. The specific aims must target
one or more of the areas
Proposals should focus on FA research that relies on
collaboration among investigators from at least two
different institutions. Special consideration will be given
to proposals that involve international collaborations and
bring new scientists to the FA community. The rationale
for the collaboration needs to be convincing: it must
clearly demonstrate that the research goals could not be
achieved by just one of the participating groups and
the synergy among the groups is essential for the
success of the project.
This scheme provides funding for mid-career
researchers from any discipline who have the potential
to beinternational research leaders. They will develop
their research capabilities, drive innovative programmes
of work and deliver significant shifts in understanding
related to human life, health and wellbeing.
This funding opportunity aims to support translational
research that advances the clinical application of
vascularization- and engraftment-focused strategies for
islet replacement therapy in type 1 diabetes (T1D).
Funded projects must address at least one of the
following areas: 1) define vascular features that
correlate with or predict graft function and long-term
durability; 2) advance strategies to enhance vascular
integration, perfusion and graft resilience at
extrahepatic transplant sites; or 3) advance non-
invasive technologies to monitor
neovascularization, perfusion, vascular stability, and
oxygenation in vivo.
This funding opportunity aims to support advancement
of cutting-edge organoid- and organ on a chip-based
disease models of Type I Diabetes (T1D). This initiative
aims to validate and refine existing human-relevant in
vitro models of T1D as tools for evaluation of
pharmacological and genetic interventions with the goal
of accelerating translation to clinical studies.
The call aims to address the following research
priorities:
· AI-powered networks for secure, efficient, and
adaptive telecommunications
·Exploring how 6G technologies can expand/enhance
daily-life applications beyond the capabilities of 4G/5G
· Advancing research on the challenges and solutions for
seamless hybrid satellite/cellular/fiber networks
·Investigating quantum computing penetration and its
implications for existing network architectures
The call aims to address the following research
priorities:
· Epidemiological Studies on Mental and Neurological
Disorders in Qatar
· Precision Mental and Neurological Health
· Emerging Technologies for Mental and Neurological
Health
. Neuromodulation and Behavioral Therapies
· Neurodevelopmental Research and Early Interventions
The call aims to address the following research
priorities:
· Artificial Intelligence, Informatics, and Technology
Solutions in Precision Medicine
· Disease Risk Stratification in Population Groups
· Integration of Genomics and other Omics in Clinical
Diagnostics
· Pharmacogenomics from Discovery to Implementation
The call aims to address the following research priority:
· Smart Integrated Disease Management (IDM) for
Protected Vegetable Production
· Resilient, Traceable, and Allergen-Safe Supply Chains
for Specialty-Nutrition Foods
· Agricultural policies and Agricultural Extension
· Digital Agriculture and Food System Innovation
The aim is to support investigator-initiated trials to
undertake (1) innovative clinical studies using novel
agents, novel combination therapies, or
immunotherapies with high potential for clinical activity
in WM; and (2) studies that substantially improve
quality of life and/or reduce prevalent disease
complications. It is seeking distinctly novel advances
and innovative approaches.
The IWMF seeks proposals to understand the
mechanisms of Waldenstrom macroglobulinemia
pathogenesis with a focus on (1) uncovering new
features of WM biology and cellular vulnerabilities; (2)
laboratory studies investigating mechanisms of WM
relapse and therapy resistance; and (3) identifying
novel, therapeutically exploitable targets that represent
previously under-explored opportunities. Such
foundational studies should be focused on translational
potential and ultimately driven by the goals of improved
patient outcomes and reduction or elimination of
disease.
IWMF seeks to support correlative companion research
studies within pharmaceutical and biotechnology
company-sponsored trials for Waldenstrom
macroglobulinemia patients that will be instrumental in
determining the optimal use of new therapeutics under
study. These projects leverage biological samples
collected during trials to explore and validate
biomarkers, mechanisms of response or resistance, or
disease biology response to therapeutic intervention
that will inform future clinical studies. Projects may
include identifying genetic, proteomic, or immune
markers that predict activity profiles, elucidating
molecular mechanisms of resistance, TME
profiling, MRD assessment, among others.
These grants aim to support research studies to (1)
accelerate existing and additional IWMF Grants requiring
further funding based on a novel, testable hypothesis
that drives the additional funded research work toward
translational and clinical applications (an Acceleration
Grant); or (2) expand funding support for novel,
translational mechanisms or targets, based on previous
proof-of-concept work that may or may not have
previous evidence of activity in B-cell malignancies (an
Expansion Grant).
The aim of this grant is to provide support to talented
young investigators with a background in hematology
and/or oncology, encouraging them to either enter or
continue WM research. A successful applicant’s
academic program must have a formal teaching
curriculum and mentoring from established investigators
with a proven record of advancing relevant research in
the B-cell malignancy or plasma cell malignancy field.
The Foundation for Prader-Willi Research (FPWR) is
dedicated to supporting research to advance the
understanding and treatment of Prader-Willi syndrome
(PWS). Briefly, funding priority areas include:
(1) Genotype to phenotype: understanding PWS
genetics / how loss of PWS-critical region genes leads to
the phenotype, (2) Neurobiology of hunger / feeding
behavior and metabolism in PWS, (3) Neurobiology of
cognition, maladaptive behavior, and mental health in
PWS, (4) Clinical care research: evaluation of existing
drugs and interventions to improve the significant
clinical concerns in PWS and (5) Therapeutics
development for PWS- Genetic therapies; novel or
repurposed pharmaceuticals; and devices
The aim of this RFP is to further develop and validate
established biomarkers for which there is a clear clinical
need in Alzheimer's disease and related dementias. This
RFP prioritizes biomarkers with a defined context of
use, a clear advantage over other relevant biomarkers,
and a path to commercialization and/or clinical use.
Specifically, this RFP focuses on: (1) Developing novel
PET ligands for clinical trials, (2) Supporting novel CSF
biomarkers, (3) Validating innovative MRI approaches in
larger cohorts and (4) Developing novel measures of
functional activity such as EEG
This scheme provides funding for early-career
researchers from any discipline who are ready to
develop their research identity. Through innovative
projects, they will deliver shifts in understanding related
to human life, health and wellbeing. By the end of the
award, they will be ready to lead their own independent
research programme.
The purpose of this NOFO is to announce support for
meritorious research projects that address research
questions relevant to human dental, oral, or craniofacial
(DOC) biology, and diseases and conditions, through
analysis of existing and publicly available genomic data,
with or without other types of complementary data,
using statistical and computational approaches. Projects
aimed at understanding oral health disparities to inform
strategies for improving health for all individuals are a
priority. Projects focused on investigating and/or
characterizing human biological pathways to inform
identification of intervention targets or defining the
pathogenicity of known genetic variants are encouraged.
The purpose of this notice of funding opportunity
(NOFO) is to support efficient and innovative natural
history studies that advance medical product
development in rare diseases/conditions with unmet
needs. Through the support of natural history studies
with high quality and interpretable data elements, FDA
expects to address critical knowledge gaps, remove
major barriers to progress in the field, exert a significant
and broad impact on a specific rare disease or multiple
rare diseases with similar pathophysiology, and facilitate
rare disease product development.
This grant supports early-career investigators of
exceptional creativity who propose highly innovative
research projects with the potential to impact broad,
essential areas of leukemia research. For the program to
support the best and brightest minds, applications are
sought from investigators who reflect the full diversity of
the research workforce and represent diverse
backgrounds, institutions, and geographic locations.
The Therapeutic Catalyst accelerates the translation of
laboratory discoveries into novel cancer therapeutics.
This scheme aims to de-risk early projects to facilitate
further drug discovery research, funding, or partnering.
They are seeking projects with strong therapeutic
potential to deliver patient benefit. They invite
applications for early drug discovery proposals from
across all cancer indications and modalities.
The NPF is seeking grant applications that encourage the
advancement of innovative research into psoriasis and
psoriatic arthritis. Translational Research Grants fund
research projects that focus on the rapid translation of
basic scientific discoveries into clinical applications with
a clear benefit for patients with psoriatic disease.
Review of projects prioritizes applications with a
thoughtful perspective of the translational pathway that
will be required to advance the proposed aims towards
clinical reality. Commitments to interinstitutional or
interdisciplinary research are emphasized.
The NPF is seeking grant applications that encourage the
advancement of innovative research into psoriatic
disease and related comorbidities. Discovery Grants
fund researchers to explore preliminary ideas and
conduct proof-of-concept experiments. Review of
projects prioritizes meaningful collaborations that offer
the potential to bring significant new lines of inquiry to
understanding root causes and potential cures for
psoriatic disease.
The award’s goal is to help advance junior clinical
research scientists in their professional endeavors to
cure
retinal degenerative disease by:
(1) facilitating advances in laboratory and clinical
research;
(2) elucidating the mechanism for the cause and
pathogenesis of retinal degenerative diseases;
(3) developing innovative strategies to prevent, treat
and cure these diseases.
This grant provides three years of funding for
hypothesis-driven research projects. The proposed
research must represent an innovative approach to a
major challenge in DIPG/DMG research.
The funded projects must have the potential to lead to
groundbreaking discoveries in the field and transform
our understanding of the tumorigenesis process or our
ability to treat or detect DIPG.
This grant provides three years of funding to a new
DIPG/DMG investigator for hypothesis-driven research
projects. The investigator may be either a newly
independent researcher establishing a new DIPG/DMG
research lab, or an established researcher who has not
previously conducted brain tumor research.
This programme primarily funds preclinical and clinical
research focused on slowing, stopping, or reversing
Parkinson’s. For preclinical research, priority is given to
projects that are likely to lead to clinical trials in people
with Parkinson’s within 5 years. For clinical research, the
funder supports clinical trials and sub-studies of trials in
people with Parkinson’s. Research which is directed at
symptomatic relief is not in remit.
Proposals are sought from academic or industry
applicants for novel one-year pilot studies to investigate
a mechanism underlying autoimmune disease, identify
novel targets or mechanisms of autoimmune
pathogenesis, validate therapeutic targets, or provide
proof of concept for an innovative therapeutic strategy.
Through the Insight Awards, Breakthrough T1D, Lupus
Research Alliance, and the National MS Society seek to
co-fund projects that will obtain more specific insights
into the commonalities and differences of immune
pathways that govern autoimmune disease processes
and lay the groundwork for bringing together
investigators from across autoimmune fields and
disciplines. All project proposals should be relevant to
multiple autoimmune diseases, two of which should be
relevant to multiple sclerosis, systemic lupus
erythematosus (or one of its manifestations), and/or
type 1 diabetes. These projects should be designed to
establish a proof of concept to a future expanded
collaborative study and therefore should constitute
“step-one” of an ambitious endeavor.
This funding opportunity aims to support the
development of tolerance induction approaches for islet
cell therapy that enables graft-specific immune
protection without compromising natural immune
defenses. This call is open to both central and peripheral
tolerance induction strategies with prioritization given to
technologies closest to clinical translation.
The purpose of these grants is to support clinical
research at non-profit institutions worldwide focused on
thefield of robotic-assisted surgery. Successful proposals
will study important questions related to surgical care
and patient outcomes. The Intuitive Foundation has
identified key research areas of interest for the 2026-
2027 clinical grant programs. Principal Investigators are
encouraged – although not required – to submit
proposals that fall into one or more of the those areas.
The purpose of these grants is to support clinical
research at non-profit institutions worldwide focused on
the effect of robotic-assisted bronchoscopy in the clinical
care of patients with pulmonary disease. Successful
proposals will study important questions related to the
impacts robotic-assisted bronchoscopy on disease
diagnosis and or management or patient outcomes.
Applicants may propose projects under one of the
following options: (1) Development of exceptionally low-
cost nutrient ingredients (calcium, choline, DHA); (2)
Development of a low-cost prenatal supplement
(UNIMMAP MMS + 500 mg/day calcium); (3)
Development of an advanced prenatal supplement
(MMSplus: UNIMMAP MMS + 500 mg/day calcium + 100
mg/day nicotinamide + 450 mg/day choline + 200
mg/day DHA)
The purpose of the grant is to fund research that will
accelerate the discovery of druggable oncogenic
pathways and deliver cancer interception and cancer
prevention therapeutics for RUNX1-FPD children and
family members. It will lead to the development of
therapies for patients with RUNX1-FPD that will either
intercept the transition from a precancer state (clonal
hematopoiesis) to MDS/AML or prevent blood cancer.
The aim is to develop continuous C-peptide monitoring
(CCPM). Applications focused on early-stage
development of sensor technologies,
preclinical/feasibility studies and early-stage clinical
evaluation of CCPM technologies will be considered.
Letters of Intent (LOIs) are sought from academic and
industry applicants with
innovative approaches to develop CCPM technologies.
Examples of research appropriate for this RFA include,
but are not limited to:
• Early-stage development of sensor technologies
capable of continuous or high-frequency Cpeptide
detection
in biological fluids such as plasma or interstitial fluid.
• Preclinical development and validation of CCPM
systems.
• Feasibility studies and early-stage clinical evaluation of
CCPM technologies.
The purpose of this notice of funding opportunity
(NOFO) is to invite applications proposing innovative
analysis of existing social science, behavioral,
administrative, and neuroimaging data to study the
etiology and epidemiology of substance using behaviors
(defined as alcohol, tobacco, prescription, and other
substances) and related disorders, prevention of
substance use and HIV, and health service utilization.
This NOFO encourages the analyses of public use and
other extant community-based or clinical datasets to
their full potential in order to increase our knowledge of
etiology, trajectories of substance using behaviors and
their consequences, including morbidity and mortality,
risk and resilience in the development of
psychopathology, strategies to guide the development,
testing, implementation, and delivery of high quality,
effective and efficient services for the prevention and
treatment of substance use disorder and HIV. Primary
data collection is not allowed for applications in
response to this NOFO.
The Clinical Innovator provides funding for clinician-
scientists aiming to launch innovative phase I/II or
phase II.
clinical studies using novel immunotherapies. In addition
to the merits of the clinical and scientific rationale,
studies will be selected based on their novelty,
feasibility, and clinical impact.
EREF has established three key research priorities. The
decision comes in response to the urgent need for
innovative solutions and a deeper understanding of
these pressing environmental challenges. The three
selected areas represent some of the most significant
issues affecting resource management and the
environment today.
(1) Climate Change Impacts/Greenhouse Gas Emissions
(2) Emerging Contaminants
(3) Advancing Materials Circularity & Recycling
The AABB Foundation awards grants for investigator-
initiated original research in all aspects of blood
banking, transfusion medicine and biotherapies.
Research content areas eligible for the grant program
include the
following: Immunology, Hematology,
Immunohematology, Infectious Diseases, Biotherapies,
and Patient Blood
Management. Applications for research into innovative
and new projects are a priority.
These support clinical or fundamental research projects
focused on human gut microbiota related to health and
disease. For the current round, project must focus on
what perturbations may involve, but not exclusively,
drugs, lifestyle factors, smoking, etc. The project should
address mechanisms. Funding should not be used for a
randomized controlled trial but can include the use/
analysis of samples collected from clinical trials.
The aim is to progress the understanding of the
mechanisms that contribute to the variable clinical
presentation of PTEN hamartoma tumour syndrome
(PHTS). Research proposals should focus on one of the
following aims:
(1) Explore opportunities to identify and/or undertake
preliminary validation of biomarkers for PHTS that could
predict symptom onset, occurrence, or
progression/severity of symptoms at the individual level.
(2) Elucidate the mechanisms of clinical heterogeneity
that may include assessment of how different PTEN
variants and other genetic, molecular, or cellular
mechanisms contribute to and are associated with the
clinical spectrum associated with PHTS.
Pfizer and the CanAge are collaborating to offer a new
grant opportunity seeking grant proposals for programs
that seek to explore innovative approaches to persistent
challenges impacting older adults living with rare
diseases, including, but not limited to:
• Accelerating time to diagnosis by increasing
understanding of the symptoms (including the
distinctions
between ageing and illness) through enhanced clinical
awareness and integration of genetic testing to identify
underlying conditions earlier
• Supporting development of National Action Plans on
Rare Disease (RD) to including solutions for the specific
challenges faced by older adults and communities
ageing with RD
• Gathering exisiting evidence to support advocacy for
closing heatlhcare gaps and drive policy change
This program supports an innovative and collaborative
group of researchers working together to improve our
understanding of the biological mechanisms that
underlie bipolar disorder. BD2 will fund teams of
multidisciplinary scientists to develop targeted and
groundbreaking research applications that will examine
the genetic, molecular, cellular, circuit, and/or behavioral
mechanisms of bipolar disorder.
This scheme provides funding for mid-career
researchers from any discipline who have the potential
to be international research leaders. They will develop
their research capabilities, drive innovative programmes
of work and deliver significant shifts in understanding
related to human life, health and wellbeing.
The MDx Impact Grants aim to unlock the potential of
PCR to democratise access to accurate diagnostic tests
that improve patient outcomes. The goal is to develop
tests that address unmet clinical needs. The programme
provides researchers with access to Seegene’s
syndromic PCR technology and development grants to
perform clinical studies.
These grants are intended to facilitate research that will
contribute to the development of new therapies or
therapeutic strategies to treat CF, with an emphasis on
advancing CFTR gene repair and replacement
approaches. Collaborations that bring new investigators
and technologies into the CF research community will
be given highest priority. Proposals must include
preliminary data to justify support from the Cystic
Fibrosis
Foundation.
The Well-Being in FTD Pilot Grant supports research to
improve the well-being of persons diagnosed, families,
and caregivers and to improve access to equitable, high-
quality diagnosis, care, support, and research
participation options. Please refer to the link below for
examples of suitable research topics.
The aim is to support innovative research that advances
the clinical translation of biomaterial-based immune-
isolation strategies for islet cell replacement therapy in
T1D. Preference will be given to proposals that:
Use GMP-compatible biomaterials to enhance clinical
relevance, Include benchmarking against
biomaterials/devices with prior clinical testing, Use large
animal models and NHPs, Involve collaborations
between teams that have tested devices in preclinical
models and can compile data towards better
mechanistic understanding of the FBR or Build on
previous clinical studies and/or explanted devices to
elucidate mechanisms of human FBR
This award provides seed funding to address the gap
between technology development and clinical application
of cancer immunotherapies. These grants aim to
encourage collaboration between technology developers
and clinical cancer immunologists and to generate the
proof-of-principle of a novel platform technology in
bioinformatics, ex vivo or in silico modeling systems,
immunological or tumor profiling instrumentation,
methods, reagents and assays, or other relevant
technologies that can enable clinician scientists to
generate deeper insights into the mechanisms of action
of effective or ineffective cancer immunotherapie
Awarded to investigators at any level, these grants
provide seed funding for new projects that have the
potential to lead to larger investigations. These grants
typically entail feasibility studies rather than hypothesis-
driven research. Examples include manual development
and new biomarker development.
Applications addressing the priorities set out by the
National Action Alliance for Suicide Prevention’s
Research.Prioritization Task Force are encouraged.
Priority area research applications are reviewed along
with the general pool of grant applications, with priority
given to strong grants in the designated areas.
The purpose of this Notice of Funding Opportunity
(NOFO) is to support and facilitate multidisciplinary
approaches towards the development of new and/or
improved contraceptive methods for both men and
women through the formation of a Contraceptive
Development Research Center. This NOFO also allows
the inclusion of translational studies to facilitate the pre-
clinical to clinical transition and increase the likelihood of
clinical success.
The IETF is requesting proposals for grants addressing
the etiology and pathogenesis of essential tremor.
Concise, clearly written proposals that are hypothesis-
driven have the best chance of being funded.
Applications should focus on studies achieving one or
more of the following goals:
1) A better understanding of the underlying
pathophysiology of ET, including independent validation
of previous
findings.
2) A better understanding of the etiology of ET
3) Development or further validation of animal models
of ET
Proposals should address key outstanding questions and
have the potential to lead to a challenge or a change
in the current paradigm or conventional wisdom and/or
lead to a groundbreaking discovery. Preliminary data is
not required in the proposal, but the underlying concept,
premise or hypothesis must be plausible and testable,
and the proposal must be focused with a well-defined
goal that is achievable within the timeframe and amount
of the award.
The purpose of this Notice of Funding Opportunity (FOA)
is to enhance mechanistic and epidemiologic
investigations addressing the roles of co-infection and
cancer to shed light on presently unestablished
pathways in carcinogenesis that may inform prevention
and treatment strategies for infection-related cancers.
Preference will be given to investigations of co-infections
with known oncogenic agents (excluding human
immunodeficiency virus [HIV]) and of co-infections that
engender novel opportunities for prevention and
treatment.
The Disease Model Award is designed to advance the
field by developing and validating innovative models to
support the scientific community in accelerating
discovery. Applications must focus on disease models
and their validation. Proposals primarily centered on
therapeutic development research are out of scope for
this program and will not be reviewed. The goal is to
develop, validate, or utilize non-rodent disease models
(in silico, in vitro, or in vivo) for therapeutic
development for IRD and dAMD.
The Polio Research Committee is calling for research
proposals supporting the Polio Endgame Strategy 2022-
2026. Research proposals supporting the strategic plan
may be submitted to the Committee for review and
funding. Preference will be given to proposals developed
by GPEI partner agencies and their research
collaborators. However, other institutions may also
submit proposals if they address their research
priorities.
The purpose of this NOFO is to encourage applications
to phenotype and/or perform research on embryonic
lethal knockout (KO) mouse strains being generated
through the International Mouse Phenotyping
Consortium (IMPC) of which the NIH Knockout Mouse
Phenotyping Program (KOMP2) is a member. The
mission of IMPC is to generate a comprehensive
catalogue of mammalian gene function that will provide
the foundation for functional analyses of human genetic
variation.
Cure SMA encourages applications on novel research
that will enhance the understanding of SMA disease
pathology at the molecular, cellular, and biochemical
level; generate key reagents and tools to facilitate drug
development and clinical trials; and identify new
therapeutic strategies for SMA. Particular interests exist
in understanding mechanisms underlying the pathology
of disease and/or identifying drug targets synergistic
with SMN-upregulating therapeutics for use in
older/symptomatic patients.
Well-suited applications must propose the development
of technologies that offer the potential to accelerate
and/or enhance research in the areas of cancer biology,
early detection and screening, clinical diagnosis,
treatment, cancer control, epidemiology, and/or address
issues associated with cancer health disparities.
Technologies proposed for development may be
intended to have widespread applicability but must be
focused on improving molecular and/or cellular
characterizations of cancer biology.
The National Cancer Institute (NCI) invites grant
applications proposing exploratory research projects
focused on further development and validation of
emerging technologies offering novel capabilities for
targeting, probing, or assessing molecular and cellular
features of cancer biology for basic, clinical, or
epidemiological cancer research.
This NOFO solicits applications for support of
exploratory/developmental studies aimed at accelerating
progress toward understanding, preventing or treating
Guillain Barre Syndrome (GBS) and/or Chronic
Inflammatory Demyelinating Polyneuropathy (CIDP).
Innovative studies of disease mechanisms, susceptibility
factors, model systems, biomarkers and treatments are
encouraged.
The fiscal year 2025 (FY25) Prostate Cancer Research
Program (PCRP) Idea Development Award (IDA)
supports new ideas that represent innovative
approaches to prostate cancer research and have the
potential to make an important contribution to the PCRP
mission. All applications are required to address one or
more of the FY25 PCRP Overarching Challenges.
The fiscal year 2025 (FY25) Prostate Cancer Research
Program (PCRP) Clinical Consortium Award (CCA)
provides support to develop, maintain, and enhance the
necessary collaborations and resources to rapidly
execute phase 2 and/or phase 2-linked phase 1
(phase1/2) prostate cancer clinical trials. The primary
intent of the PCRP Clinical Consortium Award is to
combine the efforts of leading investigators across
multiple institutions to expedite the clinical
advancement of novel therapeutic interventions in
prostate cancer to decrease the impact of the disease.
Research Grant Awards are intended for established,
experienced, independent investigators affiliated with a
research or academic institution whose proposed
projects investigate hypotheses directly related to
Dravet syndrome. Proposals are scored according to NIH
guidelines based on the quality of preliminary data,
research design, feasibility, investigator’s qualifications,
and overall impact. Grants are awarded for $250,000
over 2 years (beginning January 1 of each year), with
indirect costs not to exceed 10% of the award.
Transformational Science Grants are intended for
established, experienced, independent investigators
affiliated with a research or academic institution whose
proposed projects have substantial preliminary data,
investigate hypotheses directly related to Dravet
syndrome, and have potential to significantly impact the
field of research.
Vision Grants are intended to provide initial funding
for novel, innovative research by promising young
investigators that will advance progress towards
detection, prevention, or treatment of preeclampsia,
HELLP syndrome, and other hypertensive disorders of
pregnancy. Post-doctoral, Clinical Fellows, or Early Stage
Investigators only are eligible to apply.
This award is intended to promote research in topic
areas of special interest that relate to NEA’s
advancement of our overall research priorities for
eczema. The availability of this grant category will be
determined on an annual basis; topics of special interest
may vary. For 2025, specific areas of research interest
include: patient-centered outcomes research.
This award provides funding support for experienced
researchers with recognized productivity — either within
or outside the eczema field — to conduct highly
innovative, cutting-edge investigations related to
eczema. Data from this award can then be used to seek
additional, larger-scale funding from the National
Institutes of Health (NIH) or other funding entities to
build on these discoveries.
Notice of special interest – accelerating progress in
celiac disease research funding opportunity. This
supports research on the etiology and pathogenesis of
celiac disease, identification of therapeutic targets, and
development of preventative or disease ameliorating
therapies and strategies. Each institute has its own
research priorities.
To make grants to fund relevant nutritional research.
To support programs for the education and training of
mothers during pregnancy and after the birth of their
children, so that good nutritional habits can be formed
at an early age.
To assist in the training of persons to work as
educators and demonstrators of good nutritional
practices.
To encourage the...
The purpose of the Fogarty Emerging Global Leader
Award is to provide research support and protected time
(three to five years) to an early career research
scientist from a low- or middle-income country (LMIC)
who holds a junior faculty position at an LMIC academic
or research institution, as defined by the World Bank...
The Wings for Life invites executive summaries for its
project research grants. These support basic or clinical
research projects related to spinal cord injury with the
perspective to improve outcomes. Projects may be in
the following areas:
• basic research projects – nerve regeneration and
plasticity, neuronal and glial protection, functional
deficits induced by...
These support research that accelerate the
understanding of the biological mechanisms underlying
Alzheimer’s disease and related dementias as well as
innovative approaches to better diagnose, prevent, or
delay the progress of the disease. The awards are
designed for researchers who have already generated
some amount of preliminary data but are...
EFSD/Lilly exploring and applying new strategies in
diabetes expand the program. This supports diabetes
research projects on potential strategies that can be
implemented in Europe and rolled out in low and
middle-income countries to favor the improvement of
quality of care for people living with diabetes.
Research addressing the most intractable issues in
paediatric cancer. Projects should fall under the
following research themes: developmental origins of
paediatric cancers; drugging currently undruggable
paediatric cancers; developing novel immunotherapies;
or discovery and development of novel paediatric cancer
drug targets.
Research projects on Down’s syndrome. Applications
may cover fundamental, translational, epidemiological,
clinical research, neurobiology and pharmacology,
genetic, genomic, induced pluripotent stem cells,
neuropsychology techniques or data analysis. Priority
will be given to clinical research projects.
Closing knowledge gaps in transthyretin
cardiomyopathy in emerging markets under its
competitive grants program. This supports projects that
focus on closing the knowledge gaps in transthyretin
cardiomyopathy within Asia, Latin America, Africa, and
Middle East. Projects should focus on:
educating healthcare providers on the subject matter;
creating strategies...
COVID-19 Epidemiology Research Projects that will be
considered for Pfizer support should be focusing on
SARS-CoV-2 Variants epidemiology, T-cell responses to
SARS-CoV-2 – from natural infection or Paediatric
COVID-19 epidemiology – in children and
adolescents <16 years, characterization of disease
burden and epidemiology.
Support research-training programs that focus on: -
Major endemic or life-threatening emerging infectious
diseases, Neglected tropical diseases, Infections that
frequently occur as co-infections in HIV
infected individuals or Infections associated with non-
communicable disease conditions of public health
importance in LMICs.
This opportunity fosters research in the areas of early
OA and prevention of OA progression. Proposed studies
need not relate specifically to sports injuries. Research
priorities include:
Investigating the pre-osteoarthritic joint;
Examining prevention or treatment of posttraumatic
OA;
Determining the relationship between injury and OA;
Enhancing clinical...
Supports research focusing on osteoarthritis and chronic
pain associated with osteoarthritis, as well as patient-
centered standard of care and management. Research
may include pain and function, the biopsychosocial
aspects of the disease, the complexities, and challenges
of care, and the future of osteoarthritis and
osteoarthritis pain management. Programs...
William E Paul distinguished innovator award in
lupus and autoimmunity. This supports novel research
into the fundamental causes of lupus to provide new
directions toward a cure. Novel, hypothesis or
discovery-driven proposals using clinically relevant
models in lupus research are welcome. Proposals must
aim to uncover the fundamental causes of lupus and...
HEALTHLINE and their reporter's teams are doing an
outstanding job, particularly, in these difficult
challenging existential times. Covid-19 pandemic is
ravaging the world reaping lives without distinction
between races, languages, nationalities,
social level, faith, and religion. Thanks to HEALTHLINE
for the great job they are offering to the community and
for the daily updates spreading the right information
and saving lives.
These enable members to undertake research activities
and network among centers at an international level.
Activities may include interactive educational events
and clinical networks. Proposals relevant to the society’s
activities, such as the validation of guidelines, or clinical
networks for testing treatment regimes or disease
management, are encouraged.
